THDP-17 is a novel glutaminase activity inhibitor, showing a partial uncompetitive inhibition in vitro and a significant reduction of ammonia and glutamate production in vivo. References: Díaz-Herrero MM, del Campo JA, Carbonero-Aguilar P, Vega-Pérez JM, Iglesias-Guerra F, Perinán I, Minano FJ, Bautista J, Romero-Gómez M. THDP17 decreases ammonia production through glutaminase inhibition. A new drug for hepatic encephalopathy therapy. PLoS One. 2014 Oct 17;9(10):e109787. doi: 10.1371/journal.pone.0109787. eCollection 2014. PubMed PMID: 25329718; PubMed Central PMCID: PMC4201470.
纯度:≥98%
CAS:104741-27-7