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Filibuvir
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Filibuvir图片
CAS NO:877130-28-4
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍

Filibuvir (PF00868554; PF-00868554) is a novel and potent NS5B inhibitor of the non-nucleoside inhibitor (NNI) class developed for the treatment of hepatitis C. It inhibits the HCV nonstructural 5B protein (NS5B) RNA-dependent RNA polymerase, by binding noncovalently in the non-catalytic “Thumb 2” allosteric pocket of NS5B and causes a decrease in viral RNA synthesis. In vitro, filibuvir is equipotent against genotype 1a and 1b replicons, with an EC50 of 59 nM.

纯度:≥98%

CAS:877130-28-4