ONO-1714 is a inducible nitric oxide synthase (NOS-2) inhibitor potentially for the treatment of hypotension. ONO-1714 attenuates inflammation-related large bowel carcinogenesis in male Apc(Min/+) mice. ONO-1714 reduces hyperoxic lung injury in mice. ONO-1714 inhibits neuronal NOS and exerts antinociception in rats. References: Pozo-Rodrigálvarez A, Gradillas A, Serrano J, Fernández AP, Martínez-Murillo R, Pérez-Castells J. New synthesis and promising neuroprotective role in experimental ischemic stroke of ONO-1714. Eur J Med Chem. 2012 Aug;54:439-46. doi: 10.1016/j.ejmech.2012.05.031. PubMed PMID: 22703704.
纯度:≥98%
CAS:214479-33-1