ETP-45658 is a PI3-kinase inhibitor, also ihibiting DNA-PK and mTOR. References: Hill R, Kalathur RK, Callejas S, Colaco L, Brandao R, Serelde B, Cebriá A, Blanco-Aparicio C, Pastor J, Futschik M, Dopazo A, Link W. A novel phosphatidylinositol 3-kinase (PI3K) inhibitor directs a potent FOXO-dependent, p53-independent cell cycle arrest phenotype characterized by the differential induction of a subset of FOXO-regulated genes. Breast Cancer Res. 2014 Dec 9;16(6):482. doi: 10.1186/s13058-014-0482-y. PubMed PMID: 25488803; PubMed Central PMCID: PMC4303209.
纯度:≥98%
CAS:1198357-79-7