Methotrexate 5-methyl ester is an impurity of Methotrexate, a folic acid antagonist. Used as a antineoplastic and antirheumatic. References: Witt TL, Stapels SE, Matherly LH. Restoration of transport activity by co-expression of human reduced folate carrier half-molecules in transport-impaired K562 cells: localization of a substrate binding domain to transmembrane domains 7-12. J Biol Chem. 2004 Nov 5;279(45):46755-63. Epub 2004 Aug 26. PubMed PMID: 15337749.
纯度:≥98%
CAS:67022-39-3