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Tilisolol HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:62774-96-3
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Tilisolol, formerly known as N-696, is a nonselective beta-adrenergic blocker. Tilisolol hydrochloride dilates coronary arteries through an ATP-sensitive K(+)-channel opening mechanism in dogs. In contrast to propranolol, N-696 lowered blood pressure and heart rate without peripheral vasoconstriction and did not augment forearm vasoconstrictive responses to norepinephrine. References: Kawakami S, Ohshima N, Hirayama R, Al MH, Kitahara T, Sakaeda T, Mukai T, Nishida K, Nakamura J, Nakashima M, Sasaki H. Biodistribution and pharmacokinetics of O-palmitoyl tilisolol, a lipophilic prodrug of tilisolol, after intravenous administration in rats. Biol Pharm Bull. 2002 Aug;25(8):1072-6. PubMed PMID: 12186412.

纯度:≥98%

CAS:62774-96-3