ETC-206 is a novel, potent and selective MNK1/2 inhibitor with IC50 of 64 nM for MNK1 and IC50 of 84 nM for MNK2. When used in combination with dasatinib, ETC-206 prevents BC-CML LSC self-renewal in vitro and enhances dasatinib antitumor activity in vivo.

纯度：≥98%

CAS：1464151-33-4