TLK19781 is an insulin receptor modulator. In cultured cells made insulin resistant HIV by PI treatment, TLK19781 both increased the content of insulin-stimulated GLUT4 at the plasma membrane and enhanced insulin-stimulated glucose transport. References: Wu M, Dai G, Yao J, Hoyt S, Wang L, Mu J. Potentiation of insulin-mediated glucose lowering without elevated hypoglycemia risk by a small molecule insulin receptor modulator. PLoS One. 2015 Mar 23;10(3):e0122012. doi: 10.1371/journal.pone.0122012. eCollection 2015. PubMed PMID: 25799496; PubMed Central PMCID: PMC4370409.
纯度:≥98%
CAS:309932-60-3