TMPPAA is an allosteric agonist and positive allosteric modulator (PAM) of 5-HT3 receptor. References: Gasiorek A, Trattnig SM, Ahring PK, Kristiansen U, Frolund B, Frederiksen K, Jensen AA. Delineation of the functional properties and the mechanism of action of TMPPAA, an allosteric agonist and positive allosteric modulator of 5-HT3 receptors. Biochem Pharmacol. 2016 Jun 15;110-1192-108. doi: 10.1016/j.bcp.2016.04.004. Epub 2016 Apr 13. PubMed PMID: 27086281.
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CAS:844900-50-1