Monocrotaline(Crotaline)

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:	315-22-0
规格:	≥98%

包装与价格：

包装	价格(元)
25mg	电议
50mg	电议
100mg	电议
250mg	电议
500mg	电议
1g	电议
2g	电议

产品介绍

Monocrotaline (NSC-28693; Crotaline) is a naturally occuring pyrrolizidine alkaloid extracted from the seeds of the Crotalaria spectabilis plant, exhibiting dose-dependent cytotoxicity and causing pulmonary artery hypertension, right ventricular hypertrophy, and pathological changes in the pulmonary vasculature. However, it also has therapeutic potential against hepatocellular carcinoma. It acts against p53, HGF and TREM1 proteins, which play a threatening role in causing hepatocellular carcinoma. It is a novel scaffold for liver cancer with superior efficacy and lesser side effects. A

理化性质和储存条件

Molecular Formula: C16H23NO6;

Exact Mass: 325.1525
Molecular Weight: 325.36
Synonym: NSC-28693; Crotaline; NSC 28693; NSC28693

Chemical Name: 20-Norcrotalanan-11,15-dione, 14,19-dihydro-12,13-dihydroxy-, (13-alpha,14-alpha)- (9CI)

InChi Key: QVCMHGGNRFRMAD-XFGHUUIASA-N

InChi Code: InChI=1S/C16H23NO6/c1-9-13(18)23-11-5-7-17-6-4-10(12(11)17)8-22-14(19)16(3,21)15(9,2)20/h4,9,11-12,20-21H,5-8H2,1-3H3/t9-,11+,12+,15+,16-/m0/s1

SMILES Code: O=C(O[C@]1([H])CCN2[C@]1([H])C(CO3)=CC2)[C@H](C)[C@@](C)(O)[C@@](C)(O)C3=O