Description: Dutogliptin tartrate, the tartrate salt of Dutogliptin (formerly PHX-1149; PHX1149), is an orally bioavailable dipeptidyl peptidase-4 (DPP4) inhibitor with antidiabetic effects. It has exhibited improved glycemic control in type 2 diabetic patients.
References:
[1]. Population pharmacokinetic analysis of dutogliptin, a selective dipeptidyl peptidase-4 inhibitor. Clin Pharmacol Drug Dev. 2014 Jul;3(4):297-304.
[2]. Dutogliptin, a selective DPP4 inhibitor, improves glycaemic control in patients with type 2 diabetes: a 12-week, double-blind, randomized, placebo-controlled, multicentre trial. Diabetes Obes Metab. 2010 Apr;12(4):348-55
Related CAS #: 890402-81-0 (tartrate) 852329-66-9 (free base)