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Doxepin hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1229-29-4
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Doxepin hydrochloride is a highly potent Histamine H1 Receptor (histamine H1) antagonist. Doxepin hydrochloride also binds to histamine H4 receptor. Doxepin hydrochloride is an inhibitor of AR and mAChR. Doxepin Hydrochloride is a dibenzoxepin analogue and tricyclic antidepressant with antipruritic and sedative activities. Doxepin also has antagonistic effects on histamine (H1 and H2), 5-HT2, alpha-1 adrenergic, and muscarinic receptors. The antipruritic effect of this agent is the result mediated through inhibition of histamine receptors. References: Rahman N, Siddiqui S, Azmi SN. Spectrofluorimetric method for the determination of doxepin hydrochloride in commercial dosage forms. AAPS PharmSciTech. 2009;10(4):1381-7. doi: 10.1208/s12249-009-9341-z. Epub 2009 Nov 21. PubMed PMID: 19936937; PubMed Central PMCID: PMC2799607.

纯度:≥98%

CAS:1229-29-4