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Meclofenamate sodium hydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:67254-91-5
规格:≥98%
包装与价格:
包装价格(元)
2g电议
5g电议
10g电议

产品介绍

Description: Meclofenamate Sodium hydrate (Meclofenamic acid sodium hydrate) is a potent nonsteroidal anti-inflammatory drug (NSAID), acting as a dual COX-1/COX-2 inhibitor with IC50 of 40 nM and 50 nM, respectively. It is used in the treatment of joint, muscular pain, arthritis and dysmenorrhea. Meclofenamate sodium is a potent nonsteroidal antiinflammatory agent, specifically inhibits chemotactic factor-induced human polymorphonuclear leukocyte functions: chemotaxis, degranulation, and generation of superoxide anion radicals. These effects of MSM were found to be dependent upon the concentrations of drug not bound to albumin (free drug), and were caused by its ability to interfere at both a receptor and post-receptor level.

References: J Mol Cell Cardiol. 2016 May;94:131-44;

Related CAS#: 644-62-2 (free acid); 67254-91-5 (sodium hydrate); 6385-02-0 (Meclofenamate Sodium)

纯度:≥98%

CAS:67254-91-5