Difenamizole is a non-steroidal anti-inflammatory drug (NSAID) and analgesic of the pyrazolone group related to metamizole. It has monoaminergic properties, including inhibition of monoamine oxidase, augmentation of pargyline-induced elevation of striatal dopamine levels, inhibition of K+-induced striatal dopamine release, and inhibition of the reuptake of dopamine. References: Kameyama T, Nabeshima T, Yoshida N, Yamaguchi K. Neurochemical studies of an analgesic, 1,3-diphenyl-5-(2-dimethylaminopropionamide)-pyrazole [difenamizole]. Res Commun Chem Pathol Pharmacol. 1981 Jan;31(1):31-53. PubMed PMID: 6454942.
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CAS:20170-20-1