Bulaquine is a analogue of 8-aminoquinoline. It possesses potent activity against hepatic stages of plasmodia and hypnozoites of Plasmodium vivax and Plasmodium ovale. There were gene expression alterations in transcription, protein biosynthesis, intracellular signalling, cell division, protein ubiquitination, transcription regulation and steroid biosynthesis. The chemical showed an absence of traditional markers of hepatic stress. References: Dwivedi AK, Saxena D, Singh S. HPLC and HPTLC assays for the antimalarial agents chloroquine, primaquine and bulaquine. J Pharm Biomed Anal. 2003 Nov 24;33(4):851-8. PubMed PMID: 14623615.

纯度：≥98%

CAS：79781-00-3