PD-1-IN-2898 (2989 is the last four digits of the CAS #), a [1,2,4]triazolo[4,3- a]pyridine analog, is a novel and potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM. Inhibition of the programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction using small-molecule inhibitors is an emerging immunotherapeutic approach.
理化性质和储存条件
| Molecular Weight: 459.50 Formula: C25H25N5O4 CAS No.: 2349372-98-9 SMILES: CC1=C(NC(C2=CC(CNCCO)=CN3C2=NN=C3)=O)C=CC=C1C4=CC5=C(OCCO5)C=C4 |
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Storage | -20℃ for 3 years in powder form |
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-80℃ for 2 years in solvent |
Technical Information | PD-1-IN-2898 |
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