Dibucaine HCl (also known as Cinchocaine), a sodium channel inhibitor, is one of the most potent and toxic of the long-acting local anesthetics. Dibucaine is the active ingredient in some topical hemorrhoid creams such as Proctosedyl. It is also a component of the veterinary drug Somulose, used for euthanasia of horses and cattle. Dibucaine HCl blocks both the initiation and conduction of nerve impulses by decreasing the neuronal membrane's permeability to sodium ions. This reversibly stabilizes the membrane and inhibits depolarization, resulting in the failure of a propagated action potential and subsequent conduction blockade.

纯度：≥98%

CAS：85-79-0