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C16(PKR Inhibitor)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
C16(PKR Inhibitor)图片
CAS NO:608512-97-6
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议

产品介绍

C16 (GW-506033X; C-16; PKR Inhibitor) is a brain penetrant protein kinase (PKR) inhibitor with anti-inflammatory effects. The double-stranded RNA-dependent protein kinase (PKR), an apoptotic inducer, regulates much pro-inflammatory cytokine production. It binds the ATP-binding site of PKR and blocks autophosphorylation (IC50 =186-210 nM). It can decrease Aβ42-induced inflammatory cytokine release and apoptosis in neuronal cultures, and prevents neuroinflammation and neuronal loss in an acute excitotoxic rat model.

纯度:≥98%

CAS:608512-97-6