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C-178
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
C-178图片
CAS NO:329198-87-0
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍

C-178 is a covalent inhibitor of STING which binds to Cys91, blocking palmitoylation-induced clustering of STING. It potently and selectively suppresses the STING responses elicited by distinct bona fide activators in mouse but not human. C-178 significantly reduces STING-, but not RIG-I- or TBK1-, mediated IFN-β reporter activity. C-178 blocks palmitoylation (PMA)-induced clustering of STING; inhibits the CMA-induced phosphorylation of TBK1 (downstream protein kinase of STING).

纯度:≥98%

CAS:329198-87-0