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Desacetamidocolchicine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1420-08-2
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Desacetamidocolchicine (DAAC) is a colchicine analogue that lacks the acetamido side chain in the ring-B of colchicine. Unlike colchicine, it binds to tubulin very quickly, and yet it has powerful antimitotic properties. It has been demonstrated that the beta-tubulin isoforms differ significantly in their interactions with colchicine. References: Roychowdhury M, Sarkar N, Manna T, Bhattacharyya S, Sarkar T, Basusarkar P, Roy S, Bhattacharyya B. Sulfhydryls of tubulin. A probe to detect conformational changes of tubulin. Eur J Biochem. 2000 Jun;267(12):3469-76. PubMed PMID: 10848962.

纯度:≥98%

CAS:1420-08-2