Candoxatrilat, formerly known as U 73967 and UK69578, is an active neutral endopeptidase inhibitor that reduces degradation of atrial natriuretic peptide. Candoxatrilat reduces the clearance of atrial natriuretic factor in both intact and evidence for an extrarenal site of action. References: Kaye B, Brearley CJ, Cussans NJ, Herron M, Humphrey MJ, Mollatt AR. Formation and pharmacokinetics of the active drug candoxatrilat in mouse, rat, rabbit, dog and man following administration of the prodrug candoxatril. Xenobiotica. 1997 Oct;27(10):1091-102. PubMed PMID: 9364744.
纯度:≥98%
CAS:123122-54-3