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Caprospinol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:4952-56-1
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Caprospinol, formerly known as SP-233, is a β-Amyloid (Aβ) protein neurotoxicity inhibitor potentially for the treatment of Alzheimer's disease. Caprospinol crosses the blood-brain barrier, accumulates in the brain, and restores cognitive impairment in a pharmacological rat model of AD. Caprospinol is stable, does not bind to known steroid receptors, is devoid of mutagenic and genotoxic properties, and is devoid of acute toxicity in rodents. References: Papadopoulos V, Lecanu L. Caprospinol: discovery of a steroid drug candidate to treat Alzheimer's disease based on 22R-hydroxycholesterol structure and properties. J Neuroendocrinol. 2012 Jan;24(1):93-101. doi: 10.1111/j.1365-2826.2011.02167.x. Review. PubMed PMID: 21623958.

纯度:≥98%

CAS:4952-56-1