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E6201
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
E6201图片
CAS NO:603987-35-5
规格:≥98%
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍

E6201 (E-6201) is a novel, potent, and fungal metabolite analog and inhibitor of MEK-1/MEKK-1 (mitogen-activated protein kinase kinase 1 and mitogen-activated protein kinase kinase kinase 1) with potential antipsoriatic, anti-inflammatory and antineoplastic activities. As a novel anti-inflammatory agent, it has potent inhibitory effects on the production of proinflammatory cytokines from leukocytes and antiproliferative activity on keratinocytes. E6201 specifically binds to and inhibits the activities of MEK-1 and MEKK-1, which may result in the inhibition of tumor cell proliferation. MEK-1 and MEKK-1 are key components in the RAS/RAF/MEK/MAPK signaling pathway, which regulates cell proliferation and is frequently activated in human cancers.

纯度:≥98%

CAS:603987-35-5