CAS NO: | 1966107-70-9 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
DC-034 is a potent downregulator of MYC transcription in cancer cells by a G4-dependent mechanism, thereby selectively inhibiting MYC significantly greater than other G4-driven genes. References: Calabrese DR, Chen X, Leon EC, Gaikwad SM, Phyo Z, Hewitt WM, Alden S, Hilimire TA, He F, Michalowski AM, Simmons JK, Saunders LB, Zhang S, Connors D, Walters KJ, Mock BA, Schneekloth JS Jr. Chemical and structural studies provide a mechanistic basis for recognition of the MYC G-quadruplex. Nat Commun. 2018 Oct 12;9(1):4229. doi: 10.1038/s41467-018-06315-w. PubMed PMID: 30315240; PubMed Central PMCID: PMC6185959.
纯度:≥98%
CAS:1966107-70-9