Leucyl-leucyl-leucine is an endosome escape moiety, may be used for pH-dependent endosomal membrane disruption to release agents such as antisense oligonucleotides (AONs) inside cells. Trileucine is used to evaluate the absorption characteristics of reversed phase liquid chromatography (HPLC) media. References: Go K, Parthasarathy R. Crystal structure and a twisted beta-sheet conformation of the tripeptide L-leucyl-L-leucyl-L-leucine monohydrate trimethanol solvate: conformation analysis of tripeptides. Biopolymers. 1995 Nov;36(5):607-14. PubMed PMID: 7578952.
纯度:≥98%
CAS:10329-75-6