Cbz-B3A inhibits the phosphorylation of eIF4E-binding protein 1 (4EBP1) and blocks 68% of translation. Cbz-B3A binds to ubiquilins 1, 2, and 4. References: Coffey RT, Shi Y, Long MJ, Marr MT 2nd, Hedstrom L. Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling. J Biol Chem. 2016 Mar 4;291(10):5221-33. doi: 10.1074/jbc.M115.691584. Epub 2016 Jan 6. PubMed PMID: 26740621; PubMed Central PMCID: PMC4777855.

纯度：≥98%

CAS：1884710-81-9