CC-3052 is a water-soluble, highly stable thalidomide analogue that is a potent inhibitor of HIV-1 expression and activation-Induced TNF-α production. CC-3052 is ~200-fold more potent in inhibiting production of LPS-induced TNF-α than thalidomide. CC-3052 is also able to inhibit PHA-induced and rTNF-α-induced TNF-α transcription in PBMC as well as TNF-α transcription due to adhesion of purified monocytes to tissue culture flasks. References: Lee YK, Chung SK. The inhibitory effect of thalidomide analogue on corneal neovascularization in rabbits. Cornea. 2013 Aug;32(8):1142-8. doi: 10.1097/ICO.0b013e318292a79d. PubMed PMID: 23739149.

纯度：≥98%

CAS：216884-02-5