CCT036477 is a selective inhibitor of wingless-type MMTV integration site family (WNT)-dependent transcription. It reduces the transcriptional activity of the T-cell factor/lymphoid enhancer factor transcription factor family at the ss-catenin level. References: Barghout SH, Zepeda N, Xu Z, Steed H, Lee CH, Fu Y. Elevated β-catenin activity contributes to carboplatin resistance in A2780cp ovarian cancer cells. Biochem Biophys Res Commun. 2015 Dec 4-11;468(1-2):173-8. doi: 10.1016/j.bbrc.2015.10.138. Epub 2015 Oct 29. PubMed PMID: 26522223.
纯度:≥98%
CAS:305372-78-5