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CCT241736
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1402709-93-6
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

CCT241736 is a potent and orally bioavailable and dual FLT3-Aurora inhibitor. CCT241736 has IC50 against FLT3, Aurora A and Aurora B of 0.035, 0.015 and 0.1 μM respectively. CCT241736 inhibits a wide range of FLT3 mutants, including FLT3-ITD, -D835Y, -D835H, -K663Q and -N841I. In cellular assays, CCT241736 inhibits viability of the human FLT3-ITD positive AML cell lines MOLM-13 and MV-4;11 with EC50 of 0.1 and 0.27 References:

纯度:≥98%

CAS:1402709-93-6