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Guanfacine hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Guanfacine hydrochloride图片
CAS NO:29110-48-3
包装与价格:
包装价格(元)
10mg电议
50mg电议
100mg电议

产品名称
Guanfacine, Tenex, Intuniv
产品介绍

生物活性

Guanfacine hydrochloride是一种抗高血压药,是一种选择性的α2A肾上腺素受体激动剂,Kd为31 nM,选择性是α2B肾上腺素受体的60倍。

靶点信息

α2A-adrenoceptor

化学数据

目录号A15098
作用机制Agonist (激动剂)
M. Wt282.55
FormulaC9H10Cl3N3O
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.29110-48-3
SynonymsGuanfacine, Tenex, Intuniv
SMILESC1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl

溶解度

In vitroDMSO48 mg/mL (169.88 mM)
Water26 mg/mL (92.01 mM)
Ethanol48 mg/mL
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM35.39 mL176.96 mL353.92 mL
0.5 mM7.08 mL35.39 mL70.78 mL
1 mM3.54 mL17.7 mL35.39 mL
5 mM0.71 mL3.54 mL7.08 mL

*The above data is based on the productmolecular weight 282.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.