Dabuzalgron (previously codenamed R-450; Ro-115-1240) is a novel partial alphaA/IL receptor agonist that is administered in its hydrochloride form to control urethral smooth muscle contraction. The hemodynamic changes in the drug are very small and it is a potential drug for the treatment of stress urinary incontinence. References: Conlon K, Christy C, Westbrook S, Whitlock G, Roberts L, Stobie A, McMurray G. Pharmacological properties of 2-((R-5-chloro-4-methoxymethylindan-1-yl)-1H-imidazole (PF-3774076), a novel and selective alpha1A-adrenergic partial agonist, in in vitro and in vivo models of urethral function. J Pharmacol Exp Ther. 2009 Sep;330(3):892-901. doi: 10.1124/jpet.109.154963. Epub 2009 Jun 4. PubMed PMID: 19498105.

纯度：≥98%

CAS：219311-44-1