Dactylocyclines is novel tetracycline analogues produced by a Dactylosporangium sp. A screen for antibiotics with activity against tetracycline-resistant microorganisms has led to the isolation of Dactylosporangium sp. (ATCC 53693), a producer of several novel tetracycline analogues. The major fermentation products, dactylocyclines A and B, were purified and MIC values determined against tetracycline-resistant and tetracycline-sensitive Gram-positive bacteria. The dactylocyclines represent the first naturally occurring tetracycline C2 amides which lack cross resistance with tetracycline. References: Tymiak AA, Ax HA, Bolgar MS, Kahle AD, Porubcan MA, Andersen NH. Dactylocyclines, novel tetracycline derivatives produced by a Dactylosporangium sp. II. Structure elucidation. J Antibiot (Tokyo). 1992 Dec;45(12):1899-906. PubMed PMID: 1490881.

纯度：≥98%

CAS：146064-00-8