Hexamethylene bisacetamide is a HEXIM1 activator that inhibits transcription elongation factor b(P-TEFb) and modulates RNA polymerase II and mRNA synthesis. It induces differentiation and apoptosis in cancer cells. References: Nilsson LM, Green LC, Muralidharan SV, Demir D, Welin M, Bhadury J, Logan DT, Walse B, Nilsson JA. Cancer Differentiating Agent Hexamethylene Bisacetamide Inhibits BET Bromodomain Proteins. Cancer Res. 2016 Apr 15;76(8):2376-83. doi: 10.1158/0008-5472.CAN-15-2721. Epub 2016 Mar 3. PubMed PMID: 26941288.
纯度:≥98%
CAS:3073-59-4