CV-6209 is a potent antagonist of the platelet-activating factor (PAF) receptor, with IC50 of 75 and 170 nM, respectively. CV-6209 has little action on platelet aggregation induced by arachidonic acid, ADP, or collagen. CV-6209 is used to study the role of PAF receptor signaling in vitro and in vivo. References: Iwao Y, Takano T, Taneike I, Reva I, Isobe H, Zhang HM, Nishiyama A, Yamamoto T. Anti-Helicobacter pylori actions of CV-6209, a platelet-activating factor receptor antagonist. J Gen Appl Microbiol. 2013;59(2):147-52. PubMed PMID: 23759868.
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CAS:100488-87-7