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Furamidine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Furamidine图片
CAS NO:73819-26-8
规格:≥98%
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍

Description: Furamidine, an abisbenzamidine analog, is an antiparasite agent acting as an inhibitor of protein arginine methyltransferase 1 (PRMT1). Furamidine is also a competitive tyrosyl-DNA phosphodiesterase 1 (TDP-1) inhibitor.

References:

[1]. Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1. Nucleic Acids Res. 2007;35(13):4474-84.

[2]. Diamidine compounds for selective inhibition of protein arginine methyltransferase 1. J Med Chem. 2014 Mar 27;57(6):2611-22.

[3].The Topoisomerase I Inhibitor Irinotecan and the Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Furamidine Synergistically Suppress Murine Lupus Nephritis. Arthritis Rheumatol. 2015 Jul;67(7):1858-67


纯度:≥98%

CAS:73819-26-8