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CTP-499
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1268605-91-9
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

CTP-499 is a selective PDE inhibitor and deuterium-containing agent that slows the progression of type 2 diabetic kidney disease in patients with macroalbuminuria. CTP-499 is an HDX analogue and a pentoxifylline metabolite. Initial testing showed that CTP-499 slowed the negative processes in diabetic kidney disease. Concert is developing the agent as a complementary treatment along with the standard of care, angiotensin modulation with an ACEi or ARB. References: Perez-Gomez MV, Sanchez-Nino MD, Sanz AB, Martín-Cleary C, Ruiz-Ortega M, Egido J, Navarro-González JF, Ortiz A, Fernandez-Fernandez B. Horizon 2020 in Diabetic Kidney Disease: The Clinical Trial Pipeline for Add-On Therapies on Top of Renin Angiotensin System Blockade. J Clin Med. 2015 Jun 18;4(6):1325-47. doi: 10.3390/jcm4061325. Review. PubMed PMID: 26239562; PubMed Central PMCID: PMC4485003.

纯度:≥98%

CAS:1268605-91-9