U-18666A is an inhibitor of cholesterol synthesis. It acts by inhibiting desmosterol Δ24-reductase. References: Schmitt M, Dehay B, Bezard E, Garcia-Ladona FJ. U18666A, an activator of sterol regulatory element binding protein pathway, modulates presynaptic dopaminergic phenotype of SH-SY5Y neuroblastoma cells. Synapse. 2017 Sep;71(9). doi: 10.1002/syn.21980. Epub 2017 Jun 20. PubMed PMID: 28407359.
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CAS:3039-71-2