Leuprorelin (A43818; NSC377526; A-43818; NSC-377526; leuprolide acetate; Leuprorelinum; Eligard) is a gonadotrophin-releasing hormone (GnRH) analogue acting as an agonist at pituitary GnRH receptors. It has been used to treat a wide range of sex hormone-related disorders such as advanced prostatic cancer, endometriosis and precocious puberty. It acts primarily on the anterior pituitary, inducing a transient early rise in gonadotrophin release. With continued use, leuprorelin causes pituitary desensitisation and/or down-regulation, leading to suppressed circulating levels of gonadotrophins and sex hormones.

纯度：≥98%

CAS：53714-56-0