CP 99994 dihydrochloride is a high affinity NK1 antagonist (Ki = 0.145 nM in vitro). CP 99994 dihydrochloride also exhibits high ex vivo binding potency in gerbil striatum (IC50 = 36.8 nM). References: Chapman RW, House A, Liu F, Celly C, Mei H, Hey JA. Antitussive activity of the tachykinin NK1 receptor antagonist, CP-99994, in dogs. Eur J Pharmacol. 2004 Feb 6;485(1-3):329-32. PubMed PMID: 14757157.

纯度：≥98%

CAS：145148-39-6