CMP3a is a novel and potent NEK2 kinase inhibitor with anticancer activity. Glioma stem cells (GSCs) are important therapeutic targets in glioblastoma (GBM). NIMA-related kinase 2 (NEK2) is a functional binding protein of enhancer of zeste homolog 2 (EZH2) that plays a critical role in the posttranslational regulation of EZH2 protein in GSCs.
纯度:≥98%
CAS:2225902-88-3