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Clotrimazole
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:23593-75-1
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Clotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections, orally bioavailable thrush, and ringworm. It is also used to treat athlete's foot and jock itch. Clotrimazole works to kill individual Candida or fungal cells by altering the permeability of the fungal cell wall. It binds to phospholipids in the cell membrane and inhibits the biosynthesis of ergosterol and other sterols required for cell membrane production. This leads to the cell's death via loss of intracellular elements. It is on the World Health Organization's List of Essential Medicines, the most important medication needed in a basic health system. References: El-Asmar J, Gonzalez R, Bookout R, Mishra A, Kharfan-Dabaja MA. Clotrimazole troches induce supratherapeutic blood levels of sirolimus and tacrolimus in an allogeneic hematopoietic cell-transplant recipient resulting in acute kidney injury. Hematol Oncol Stem Cell Ther. 2015 Nov 27. pii: S1658-3876(15)00103-X. doi: 10.1016/j.hemonc.2015.11.001. [Epub ahead of print] PubMed PMID: 26684920.

纯度:≥98%

CAS:23593-75-1