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D21-6076
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

D21-6076 is a β-1,6-Glucan inhibitor. These inhibitors work as antifungal drugs by targeting the fungal cell wall. As glucan is a major component of the cell wall, specifically β-1,6-Glucan, these drugs can help fight fungal infections by degrading glucan or stopping production by inhibiting its synthase. D21-6076 is a pyridobenzimidazole analogue that achieves this function, and is effective against Candida strains (even fluconazole-resistant strains). As an improvement to D75-4590, it is active orally . References: Kitamura A, Higuchi S, Hata M, Kawakami K, Yoshida K, Namba K, Nakajima R. Effect of beta-1,6-glucan inhibitors on the invasion process of Candida albicans: potential mechanism of their in vivo efficacy. Antimicrob Agents Chemother. 2009 Sep;53(9):3963-71. doi: 10.1128/AAC.00435-09. Epub 2009 Jul 13. PubMed PMID: 19596881; PubMed Central PMCID: PMC2737848.

纯度:≥98%