CK548 is a novel inhibitor of actin-related protein (Arp)2/3 complex by inserting into the hydrophobic core of Arp3 and altering its conformation. References: Spear M, Guo J, Turner A, Yu D, Wang W, Meltzer B, He S, Hu X, Shang H, Kuhn J, Wu Y. HIV-1 triggers WAVE2 phosphorylation in primary CD4 T cells and macrophages, mediating Arp2/3-dependent nuclear migration. J Biol Chem. 2014 Mar 7;289(10):6949-59. doi: 10.1074/jbc.M113.492132. Epub 2014 Jan 10. PubMed PMID: 24415754; PubMed Central PMCID: PMC3945356.

纯度：≥98%

CAS：388604-55-5