Cintirorgon sodium, formerly known as LYC-55716, is the sodium salt of Cintirorgon which is a novel, potent and orally bioavailable RORgamma agonist with potential immunomodulatory and anticancer activities. LYC-55716 selectively binds to the nuclear receptor transcription factor RORg, forming a receptor complex that translocates to the nucleus, and binds to ROR response elements (ROREs), enhancing the function, proliferation and survival of type 17 T cells, including Th17 (helper T cells) and Tc17 (cytotoxic T cells).

纯度：≥98%

CAS：2055538-47-9