FT895 是一种有效的选择性 HDAC11 抑制剂，IC50 为 3 nM。
| 产品描述 | FT895 is a potent and selective HDAC11 inhibitor with an IC50 of 3 nM[1]. FT895 is a highly selective HDAC11 inhibitor showing greater than 1000-fold selectivity against the other 10 members of the HDAC family[1]. [1]. Martin MW, et al. Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11. Bioorg Med Chem Lett. 2018 Jul 1;28(12):2143-2147. |
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