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ZL0454
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
ZL0454图片
CAS NO:2229042-77-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
ZL0454是有效,选择性的含有溴结构域的蛋白质4 (BRD4)抑制剂,对BD1和BD2的IC50分别为49和32 nM 。
Cas No.2229042-77-5
分子式C18H22N4O3S
分子量374.46
溶解度DMSO : 50 mg/mL (133.53 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.

[1]. Liu Z, et al. Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation. Eur J Med Chem. 2018 May 10;151:450-461.