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SR15006
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SR15006图片
CAS NO:2505001-54-5
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
SR15006 是 Kruppel-like factor 5 (KLF5) 的抑制剂剂 (在 DLD-1 CRC 细胞的中,IC50 = 41.6 nM)。
Cas No.2505001-54-5
分子式C16H20ClN3O4S
分子量385.87
溶解度DMSO : 100 mg/mL (259.15 mM; Need ultrasonic)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

SR15006 is a inhibitor of KrÜppel-like factor 5 (KLF5) with an IC50 of 41.6 nM in DLD-1/pGL4.18hKLF5p cells)[1].

SR15006 (1 μM or 10 μM; DLD-1 CRC cells) causes a significant reduction in the levels of tested cyclins over the course of 72 hours[1].

[1]. Kim J, et al. The Novel Small-Molecule SR18662 Efficiently Inhibits the Growth of Colorectal Cancer In Vitro and In Vivo. Mol Cancer Ther. 2019;18(11):1973-1984.