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SNIPER(ABL)-020
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SNIPER(ABL)-020图片
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
SNIPER(ABL)-020,由 Dasatinib (ABL 抑制剂) 通过 linker 与 Bestatin (IAP 配体) 组合而成,可有效降解 BCR-ABL 蛋白。
分子式C44H59ClN10O8S
分子量923.52
溶解度DMSO : 200 mg/mL (216.56 mM; Need ultrasonic)
储存条件Store at -20°C, stored under nitrogen
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

SNIPER(ABL)-020, conjugating Dasatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein[1].

[1]. Shibata N, et al. Development of protein degradation inducers of oncogenic BCR-ABL protein by conjugation of ABL kinase inhibitors and IAP ligands. Cancer Sci. 2017 Aug;108(8):1657-1666.