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Tiazofurin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tiazofurin图片
CAS NO:60084-10-8
包装:25mg
市场价:1021元

产品介绍
Tiazofurin (NSC 286193) 是一种合成的核苷类似物,具有抗肿瘤活性。Tiazofurin 在细胞内合成为tiazole-4-carboxamide adenine dinucleotide (TAD),TAD 是 IMP 脱氢酶 (IMPDH) 的有效抑制剂。Tiazofurin 还具有抗正痘病毒 (orthopoxvirus) 和抗天花病毒活性。
Cas No.60084-10-8
别名噻唑呋林; NSC 286193; Riboxamide
分子式C9H12N2O5S
分子量260.27
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor ofIMP dehydrogenase (IMPDH)[1]. Tiazofurin also has anti-orthopoxvirusand anti-variola activities[2].

[1]. Tricot G, Jayaram HN, Weber G, Hoffman R. Tiazofurin: biological effects and clinical uses. Int J Cell Cloning. 1990;8(3):161-170.
[2]. Robert O Baker, et al. Potential antiviral therapeutics for smallpox, monkeypox and other orthopoxvirus infections. Antiviral Res. 2003 Jan;57(1-2):13-23.