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Trimethoprim-d9
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Trimethoprim-d9图片
CAS NO:1189460-62-5
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Trimethoprim-d9 是 Trimethoprim 的氘代物。Trimethoprim 是一种抑菌抗生素,也是一种具有口服活性的二氢叶酸还原酶 (dihydrofolate reductase) 抑制剂。Trimethoprim 对多种革兰氏阳性和革兰氏阴性需氧细菌 (Gram-positive 和 Gram-negative aerobic bacteria) 具有活性。Trimethoprim 可用于尿路感染,志贺氏菌病和肺孢子菌肺炎的研究。
Cas No.1189460-62-5
别名甲氧苄啶 D9
分子式C14H9D9N4O3
分子量299.37
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Trimethoprim-d9 is the deuterium labeled Trimethoprim. Trimethoprim is a bacteriostatic antibiotic and an orally activedihydrofolate reductaseinhibitor. Trimethoprim is active against a wide range ofGram-positiveandGram-negative aerobic bacteria. Trimethoprim has the potential for urinary tract infections, Shigellosis and Pneumocystis pneumonia treatment[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].